Antibody drugs such as monoclonal antibodies (mAb), bispecific antibodies, antibody-drug conjugates (ADCs), and nanobodies garnered increased interest in research and development circles. Sino ...

Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...

Monoclonal antibodies (mAbs) are manufactured proteins that behave similarly to antibodies found naturally in the body. Researchers initially developed them for treating certain cancers but have now ...

An international research team led by the University of Cologne has discovered an antibody that could advance the fight against HIV. The newly identified antibody 04_A06 proved to be particularly ...

To overcome such inherent challenges, scientists are turning to more robust molecular solutions that improve cancer cell targeting and therapeutic outcomes, among the most promising of which are ...

The oPool + display platform combines technologies to make and test large numbers of antibodies at once. Antibodies are the critical targeting agents of the immune system and the crux of immune ...

The envelope (E) proteins of Zika virus (ZIKV) and dengue virus (DENV) present a high degree of homology, which can lead to cross-reactive antibodies that exacerbate disease through antibody-dependent ...

A new approach targets the B-cell pathway with bispecific antibodies, building on decades of research that establishes the role of B cells and self-reactive antibodies in lupus, systemic sclerosis, ...